Abstract BACKGROUND: Acute kidney injury is a common complication in patients with acute heart failure. OBJECTIVE: To describe the clinical, epidemiological and laboratory characteristics of patients hospitalized due to an event of type 1 cardiorrenal syndrome. MATERIAL AND METHOD: A prospective study including patients hospitalized with acute heart failure, whose clinical diagnosis was established according to Framingham criteria. Definitive diagnosis was corroborated by echocardiography and serum levels of brain natriuretic peptide. Acute kidney injury was diagnosed and classified at admission or during hospitalization according to Acute Kidney Injury Network (AKIN). Clinical, epidemiological and laboratorial characteristics were compared between patients with and without acute kidney injury. Etiology, severity and evolution of acute kidney injury episodes were studied. The risk factors associated to acute kidney injury were studied with logistic regression analysis. RESULTS: There were included 67 patients with mean age of 66 ± 16 years and 52.2% were male. Acute kidney injury was observed in 53.7% of the patients, of whom 47.2% corresponded to episodes of AKIN 1, 27.8% to AKIN 2 and 25% to AKIN 3. Oliguric acute kidney injury was present in 33.3% of cases and 13.9% required dialysis. Renal function recovery at hospital discharge was observed in 50% of patients. The risk factors associated with acute kidney injury were: inotropic use with OR of 5.0 (95% CI 0.98-26.6, p = 0.05) and previous diagnosis of chronic renal disease with OR of 18 (95% CI, 3.6-102.2; p < 0.01). CONCLUSIONS: Acute kidney injury was a frequent complication in patients hospitalized for acute heart failure in our population. Inotropic requirement as an expression of the severity of heart failure and a history of chronic renal disease were the independently factors associated with the development of acute kidney injury.

Resumen ANTECEDENTES: La lesión renal aguda constituye una complicación frecuente en los pacientes con insuficiencia cardiaca aguda. OBJETIVO: Describir las características clínicas, epidemiológicas y de laboratorio de los pacientes hospitalizados por un episodio de síndrome cardiorrenal tipo 1. MATERIAL Y MÉTODO: Estudio prospectivo que incluyó pacientes hospitalizados por un episodio de insuficiencia cardiaca aguda, cuyo diagnóstico clínico se estableció con los criterios de Framingham y se corroboró por ecocardiografía y concentraciones séricas del péptido natriurético cerebral. La lesión renal aguda se diagnosticó y clasificó al ingreso o durante la hospitalización según criterios del Acute Kidney Injury Network (AKIN). Se compararon las características clínicas, epidemiológicas y de laboratorio entre pacientes con y sin lesión renal aguda. Los factores de riesgo asociados con lesión renal aguda se estudiaron con regresión logística. RESULTADOS: Se incluyeron 67 pacientes; la edad promedio fue de 66 ± 16 años y 52.2% eran del sexo masculino. La lesión renal aguda se observó en 53.7% de los pacientes de los que 47.2% correspondieron a episodios de AKIN 1, 27.8% a AKIN 2 y 25% a AKIN 3. El 13.9% de los episodios de lesión renal aguda requirió diálisis y 50% de los pacientes con lesión renal aguda tuvo recuperación de la función renal a su egreso. Los factores de riesgo asociados con lesión renal aguda fueron: administración de inotrópico con OR (razón de momios) de 5.0 (IC95% 0.98-26.6; p = 0.05) y el diagnóstico previo de enfermedad renal crónica con OR de 18 (IC95% 3.6-102.2; p < 0.01). CONCLUSIONES: La lesión renal aguda fue una complicación frecuente en los pacientes hospitalizados por insuficiencia cardiaca aguda en nuestra población. El requerimiento de inotrópico, como expresión de la gravedad de la insuficiencia cardiaca y el antecedente de enfermedad renal crónica fueron los factores independientemente asociados con la aparición de lesión renal aguda.

ABSTRACT Time of exposure and light intensity rearing house may affect the performance and egg quality of laying quails. This research aimed at evaluating the live performance, egg quality, biometry of the reproductive system, and the gastrointestinal tract of Japanese quails (Coturnix coturnix japonica) exposed to artificial light-emitting diodes (LED) of different colors in comparison with fluorescent lamps. A total of 240 Japanese quails were distributed in completely randomized experimental design with four treatments (fluorescent lamp, and green, red, or blue LED lamps) with six replicates of 10 birds each. Average egg weight and eggshell thickness were different (p<0.05) when LED bulbs were compared with fluorescent lamps. The egg weight of the birds exposed to the red LED was similar to those under a fluorescent lamp (p>0.05). The oviduct of 64-d-old hens exposed to green LED lighting was shorter (p<0.05) than those exposed to the fluorescent lamp. Red LED can be used to replace the fluorescent lamps, as they promote the same live performance, egg quality, and morphological development of the reproductive tract of laying Japanese quails.